Brandon Hicks hit a two-run shot off Clayton Kershaw, and Buster Posey had an RBI single for the NL West leaders, who beat the defending division champions for the seventh time in 10 this season.
The Giants finished their road trip 7-3 and played errorless ball over the last five games.
Romo (3-0) came on in the ninth to try and protect a 4-2 lead for Tim Hudson. The right-hander struck out Yasiel Puig after a one-out double by Dee Gordon, but Ramirez lined his fifth homer to left field on an 0-1 pitch. The blown was Romo’s first this season in 13 chances.
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